Investor Presentation

Strong revenue growth driven by innovation and portfolio expansion Analytics $54M 7% Chroma $36M 26% 2017 $141M Revenue R REPLIGEN Filtration $49M 35% Proteins $54M 38% 2017-2022 34% 5-year avg. annual organic growth Chroma $132M 16% Proteins $114M 14% 2022 $802M Revenue Filtration $496M 62% Long life-cycle, highly differentiated systems and consumable products 2022 total revenue reflects full year results as of our Q4 earnings call Feb. 22, 2023. 2022 franchise-level revenue and percent of total reflect franchise-level growth results as of our Q4 earnings call Feb. 22, 2023. 5

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