Equillium Results Presentation Deck
Lupus Nephritis in Numbers
equillium
50%
100,000
10-30%
< 50%
2
60%
Of systemic lupus erythematosus patients will develop lupus
nephritis, the most common severe manifestation of the disease
Lupus nephritis patients in the U.S.
Of patients will progress to end-stage renal disease requiring kidney
replacement therapy
Of patients achieve a partial response (> 50% reduction in UPCR)
after 6 months on standard of care
Approved treatments to improve standard induction therapy
Of patients fail to achieve a complete response as defined by a
UPCR of <0.5 0.7 g/g at 1 year despite new drug approvals
Parikh et al., Am J Kid Dis., 2020; Izmirly et al., Arthritis Rheumatol 2021; Rovin et al., The Lancet, 2021; Furie et al., NEJM, 2020
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