Ocuphire Pharma Investor Updates

P 27 Presbyopia - Chronic Opportunity Pupil Modulation Eye Drops May Replace Reading Glasses ● ● Nyxol's Potential Differentiated Solution "Pin-hole" effect of Nyxol and low dose pilocarpine may improve near vision by increasing depth of focus as validated by other devices/therapies More durable combination of two miotics affecting different muscles (iris dilator and sphincter) involved in pupil size modulation Tolerable use with minimal side effects expected with chronic evening use of Nyxol ee This would just become part of my daily routine for my eyes to be able to see things up close. How convenient is that? ⁹⁹ 99 Presbyopic Patient, age 49 Retinaeyedoctor.com, GlobalData Market Research Report, 2020 Large Pupil Pin-hole Pupil Near FOCUS FOCUS In focus Far In focus Ocuphire PHARMA

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