3Q22 Investor Update

JUST 18 STATES = 53% OF TOTAL U.S. CIGARETTE SALES At approximately 5.0B packs sold, just 1% market share equates to ~50M VLNⓇ packs sold Potential VLN® Distribution: MRTP States + Adjacent State Opportunities Prospective Priority Launch State Favorable MRTP Excise Tax Statute State AZ CO* CT* FL GA IL IN KY* MI* NC* NM* NY OH SC TX UT* WA* WI Total Source: CDC; Current Cigarette Use Among Adults (Behavior Risk Factor Surveillance System) 2019; World Population Review Cigarette Prices by State; Internal Documents *State with MRTP Tax Benefit % of Adult Smokers 15% 14% 12% 15% 16% 15% 19% 24% 19% 19% 16% 13% 21% 18% 15% 8% 13% 15% Pack Volume (Packs, M) 160M 130M 65M 513M 398M 253M 328M 295M 351M 500M 48M 180M 467M 215M 736M 45M 124M 184M 4,989M 22ND CENTURY GROUP Retail Sales ($B) $1.4B $1.0B $0.8B $3.9B $2.5B $2.6B $2.3B $2.0B $2.9B $3.3B $0.4B $2.2B $3.7B $1.5B $5.6B $0.4B $1.3B $1.6B $39.4B 7

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