GreenLight SPAC Presentation Deck
CBH
% BW Change from Baseline (Day 0)
MEAN ± SEM
Percentage body weight change on viral challenge
Healthy
Promising Green Light influenza vaccine candidate
High levels of antibody production and protection against viral challenge
Sick
10-
0-
-10-
-20-
-30-
0
1
T
2
Baseline
Cut-off for euthanasia
3 4 5
6
Days Post Challenge
7 8 9 10
10ug GLB quadrivalent 2 doses
1ug GLB quadrivalent 2 doses
10ug GLB quadrivalent 1 dose
Saline
Full protection against morbidity from influenza
challenge in mice, as evidenced by no loss of weight
observed in vaccinated animals
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Percent Survival
Survival post-challenge with virus
100
90-
80-
70-
60-
50-
40-
30-
20-
10-
0+
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Days Post Challenge
GLB quadrivalent candidate
GLB HA+NA candidate
Saline
Our vaccine candidates protect all mice from lethal
influenza virus challenge
HUMAN HEALTH
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