Ginkgo Results Presentation Deck

Stock-Based Compensation (Unaudited) In millions of USD Total Stock-Based Compensation Amount included in Research and Development expenses: Stock-Based Compensation Employer Payroll Taxes Related to Stock-Based Compensation Amount included in General and Administrative expenses: Stock-Based Compensation Employer Payroll Taxes Related to Stock-Based Compensation Three Months Ended June 30, 2021 $14.5 2022 $607.3 217.3 216.8 0.5 390.0 389.7 0.3 0.0 0.0 0.0 14.5 14.5 0.0 % YoY NM NM NM NM NM NM NM Six Months Ended June 30, 2022 $1,266.3 483.6 477.8 5.8 782.7 781.5 1.2 2021 $14.6 0.0 0.0 0.0 14.6 14.6 0.0 % YoY NM NM NM NM NM NM NM Modification of Equity Awards in Connection with Business Combination Prior to becoming a public company in September 2021, Ginkgo granted restricted stock units ("RSUS") with both a service-based vesting condition and a performance-based vesting condition, defined as a change in control or an initial public offering (both as defined in the underlying award agreement). Ginkgo historically did not recognize any stock-based compensation expense associated with these awards due to the performance-based vesting condition. As of December 31, 2021, there was $2.2 billion of unrecognized stock-based compensation expense related to the above catch-up adjustment for those RSUS and Earnout RSUS that had not yet fully met the service-based vesting condition as of December 31, 2021. This amount will be recognized over a weighted-average period of 1.6 years, of which $650.1 million was recognized in the first quarter and $594.0 million in the second quarter of 2022. As previously disclosed, on November 17, 2021 the board of directors modified the vesting terms of RSUs, such that Ginkgo's business combination with Soaring Eagle Acquisition Corp. was deemed to have met the performance condition for vesting. This was accounted for as a modification and resulted in a catch-up adjustment of approximately $1.5 billion of incremental stock-based compensation expense in the fourth quarter of 2021 (calculated based on the number of RSUS impacted, which had been granted since 2015, at the share price of $13.59 on November 17, 2021). Stock-based compensation expense also increased by $173.5 million in the fourth quarter of 2021 related to RSU earnout shares ("Earnout RSUS") which were also subject to the same performance condition as the underlying RSUS. 37 Property of Ginkgo Bioworks Q2 2022 UPDATE & BUSINESS REVIEW

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