Bionomics IPO Presentation Deck
Tackling the Profound Disease Burden of Post-Traumatic Stress Disorder
PTSD Represents a Significant Unmet Need
✓ 70% of people will experience a traumatic event in
their lifetime, but most people recover normally
✓ PTSD results from exposure to actual or threatened
death, serious injury or sexual violence
✓ PTSD affects up to 8% of adults during their
lifetime¹
PTSD is a global mental health problem that is
associated with significant morbidity and mortality
and shows up in all facets of peoples' lives
✓ No newly approved pharmacotherapy in almost
two decades
Medications with a novel mechanism of action that
can address the pathophysiology of PTSD are
needed
~21M
8% of adults at
some point in
their lives
~9M
3.4%
prevalence
in adults
Unmet medical need to large patient population
Advancement in care
No branded competition
Ability to potentially achieve large market share
Deck H, Mion, M, Miller, M, Weyes and Friedman M, 2013 Nation Estates of Exposure to Troumatic Events and PTSD Prevalence Using DSM-ly and DSM-5 Gr
Bionomics Journal of Traumatic Stress 2605, pp537-5422 My LM Asration A. Lande/et at Elevated Anondomide Enhanced Recall of Fear Extinction and Attemated Stress Responses Following
inhibition w/ Fatty Acid Amide Hydrolase A Rundanteed Contred Experimental Medicine Trial Bol Psychiatry 2020 M 15,876 536-54
Only 20 to 30% of PTSD patients achieve cinsicol remisionon SSR therapes
US Census Bureau //www.census.go/library/ses/2021/08/united-stones-out-population grew foster-than-nations-total population from 2010 to 2020
-7M
75% of adults
inadequately
treated
Opportunity
for BNC210
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