Bluejay Investor Presentation Deck
Symphony™M IL-6 Potential Clinical Advantages v. Current Standard Tests
Metric
Area Under Receiver Operator
Characteristic Curve (AUC)
Youden Index
Cutoff
Sensitivity
Specificity
NPV
00
Interleukin-6
(IL-6)
0.801
DIAGNOSTICS
1.52
35 pg/mL
0.89 (0.65, 0.99)
0.64 (0.55, 0.72)
0.98 (0.92, 1.00)
C-Reactive Protein
(CRP)
0.578
1.35
113.95 mg/mL
0.44 (0.22, 0.69)
0.91 (0.84, 0.95)
0.92 (0.86, 0.96)
Lactate
0.680
1.29
1.75 mmol/L
0.56 (0.31, 0.78)
0.74 (0.61, 0.84)
0.85 (0.72, 0.93)
Source: 1. Bluejay Diagnostics market research. 2. NPV = Negative Predictive Value. 3. Bluejay/Industry information, pending
the location of the testing lab. 4. from FDA Emergency Use Authorization company filings
The SymphonyTM System and SymphonyTM Cartridge have not been cleared or approved by the U.S. FDA
Sensitivity
1.0
0.8-
0.6-
0.4
0.2-
0.0-
T
1.0
ROC Curves of Biomarker Prediction of IMV
0.8
0.6
IL-6 (AUC = 0.801)
CRP (AUC = 0.578)
Lactate (AUC = 0.680)
0.4
Specificity
An analysis of the Bluejay's clinical study assessing the ability of Symphony IL-6 at time of hospital admission to predict patients at risk for
invasive mechanical ventilation (IMV) during their hospitalization demonstrated favorable clinical performance with a sensitivity of 89%,
specificity of 64%, and negative predictive value of 98%, highlighting the potential higher clinical utility of IL-6 compared to these other
standard biomarkers to identify patients at future risk of IMV.
0.2
0.0
Copyright ©2023 Bluejay Diagnostics, Inc. All rights reserved in all slides | June 2023
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