BioNTech Results Presentation Deck

Disease Horizon: Expanding the Application Spectrum of Our Technology Next Generation Immunomodulators I ■ ■ ■ Next Gen T Cell Therapies H CAR-T cells ■ mRNA Vaccines ■ Cancer Infectious Disease Autoimmunity Allergy CAR-Tregs TCR therapies Polyspecific T cell therapies Cell Therapies ▪ Cancer 1@ Targeting Disease Infectious diseases Targeted Antibodies + Immunomodulation Potently modulates innate immunity ▪ Potential for combination Small Molecule Immunomodulators Bispecifics / Trispecifics Engineered binders Enginereed MOAS ■ I Ribologicals ▪ Cancer ▪ Anti-Infectives Engineered Biologicals Grow & mature novel technologies across oncology, infectious diseases and beyond

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