Strategic Transformation 2023 slide image

Strategic Transformation 2023

Editas Medicine is a Leader in the CRISPR-based Gene Editing Medicine Field Reni-cel is an investigational gene editing medicine that is a potential "best in class" treatment for sickle cell disease and beta thalassemia Ongoing RUBY and EdiTHAL clinical trials. Editas holds exclusive foundational IP for Cas9 and Cas12a for the prevention or treatment of human disease • Source of non-dilutive capital o Recently granted sublicenses to Vertex Pharmaceuticals and Vor Bio editas MEDICINE Proprietary As Cas12a is a high fidelity and high efficiency CRISPR nuclease • Core expertise in guide RNA design and chemistry for high precision editing Longer-term focus on creating important medicines based on in vivo gene editing Scaled CMC 8.8 • Leadership team with a proven track record of drug development and commercialization 3
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