Evotec Investor Presentation Deck
iPSC Platform
evotec
¡PSC-based cell types
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PAGE 20
¡PSC-based
cell types
gene editing
ArrayCGH, karyotyping,
WGS
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IT TOTOO ID
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Delivering off-the-shelf cell therapy products to patients
EVOcells - seamless R&D continuum integrating discovery, development and manufacturing
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QC & upscaling
disease
expertise
NU
NOM
XL
Pre-clinical
development &
CMC
Single cell sequencing
3D expansion
Evotec
Clinical manufacturing
Partner
Clinical development
Upscaling
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Cell QC
pluripetency
FACE
Sede d
Cat concentration
Markers
PCR
Germer
5 Marker geres und
pee
Cleste merhaay
an
only
Calco
CC ww
OPCH
Organ
Mebl
Marker ge
Custer morphology
Cel concentration
agreed Fre
Comtrent
FACE
4 Maker poing
OPCR
Marker ge
End stage
ty
Cluster my ofen
Cel concentration
• Most advanced programme: E.iBeta - ¡PSC-based islet-like clusters mimicking human islet cells
• Partnership with Sernova - iPSC-based beta cell replacement therapy for insulin-dependent Diabetes using Sernova's
Cell Pouch™, an implantable medical device for immune protection of E.iBeta
Filing of first IND expected in 2024
• Addition of Evotec (Modena) Srl, our Evotec Cell Accelerator, secures reproducible and cGMP-compatible production
of E.iBeta batches and represents the broadest and most widely integrated cell therapy platform in the industry
Marked supply
Marketing and sales
cGMP productionView entire presentation