Bluejay Investor Presentation Deck
Symphony™M IL-6 Potential Clinical Advantages v. Current Tests Used for Sepsis Patients
IL-6 negative predictive value (NPV) superior to other standard biomarkers
Interleukin-6
(IL-6)
0.801
Metric
Area Under Receiver Operator
Characteristic Curve (AUC)
●●●
Youden Index
Cutoff
Sensitivity
Specificity
NPV
1.52
DIAGNOSTICS
35 pg/mL
0.89 (0.65, 0.99)
0.64 (0.55, 0.72)
0.98 (0.92, 1.00)
C-Reactive Protein
(CRP)
0.578
1.35
113.95 mg/mL
0.44 (0.22, 0.69)
0.91 (0.84, 0.95)
0.92 (0.86, 0.96)
Lactate
0.680
1.29
1.75 mmol/L
0.56 (0.31, 0.78)
0.74 (0.61, 0.84)
0.85 (0.72, 0.93)
Source: 1. Bluejay Diagnostics market research. 2. NPV = Negative Predictive Value. 3. Bluejay/Industry information, pending
the location of the testing lab. 4. from FDA Emergency Use Authorization company filings
The SymphonyTM System and SymphonyTM Cartridge have not been cleared or approved by the U.S. FDA
Sensitivity
1.0
0.8-
0.6-
0.4-
0.2-
0.0
1.0
ROC Curves of Biomarker Prediction of IMV
0.8
0.6
IL-6 (AUC = 0.801)
CRP (AUC = 0.578)
Lactate (AUC = 0.680)
0.4
Specificity
Bluejay clinical study assessed ability of Symphony IL-6 to predict risk for invasive mechanical ventilation (IMV) in COVID-19 patients at time of hospital
admission
Favorable clinical performance demonstrated 89% sensitivity, 64% specificity and 98% NPV, which highlights potential higher clinical utility of IL-6 compared
to other standard biomarkers to identify patients at future risk of IMV.
IMV is associated with respiratory failure, which is common in sepsis patients.
0.2
0.0
Copyright ©2023 Bluejay Diagnostics, Inc. All rights reserved in all slides | November 2023
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