Equillium Results Presentation Deck

EQUALISE Type B Interim Data Highlights Although highly proteinuric at baseline - mean UPCR 5.8 g/g - 83% of subjects had at least a partial response by week 28 and median time to response of 12 weeks 28 weeks / EOS (n = 6) 5/6 (83%) achieved complete or partial response (ORR) in UPCR by 28 weeks / EOS equillium 4/6 (67%) achieved > 80% reduction in UPCR by 28 weeks / EOS > 1 dose (n = 12) 8/12 (67%) achieved > 50% reduction in UPCR achieving at least partial response Mean proteinuria reduction of > 60% (> 3 g reduction in UPCR) Based on interim data from 2 Sep 2022-subject to change: Note: Urine protein creatinine ratio (UPCR) based on spot collection: Abbreviations: EOS: end of study: ORR overall response rate= Complete response or partial response ; EOS: end of study: UPCR urine protein creatinine ratio 31

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