Q1 2023 Earnings Presentation

APPENDIX Trailing Twelve Months Return on Invested Capital Trailing Twelve Months Ended March 31, 2023 Trailing Twelve Months Ended March 31, 2022 $529.2 $483.8 (134.8) (132.0) 394.4 351.8 [$M] Non-GAAP Operating Income Non-GAAP Income Tax Provision Non-GAAP Operating Income after Tax Average Total Invested Capital: Average Long-Term Debt Average Current Portion of Long-Term Debt Average Shareholder's Equity Less Average Cash and Cash Equivalents Total Average Invested Capital Return on Invested Capital 2023 Bruker $1,159.0 65.6 1,124.5 (707.0) 1,642.1 24.0% $962.7 59.7 1,009.9 (756.5) 1,275.8 27.6% Q1 2023 Earnings Presentation | BRUKER May 4, 2023 I 22

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