Bionomics Investor Presentation Deck

BNC210 Significantly Reduced Panic Symptoms in Humans: CCK-4-Induced Model Placebo- controlled study in 15 healthy volunteers who experienced a CCK-4-induced panic attack Bionomics Panic Symptom Scale (% of Placebo) 100 90 80 70 60 40 30 20 10 0 Total # of Panic Symptoms -37.7% (p<0.048) CCK-4 = Cholecystokinin Tetrapeptide (a peptide that induces anxiety and panic symptoms) Panic Symptom Scale (% of Placebo) Placebo 100 90 80 70 60 50 40 30 20 10 0 Panic Symptom Intensity BNC210 -52.7% (p<0.041) BNC210 demonstrated reduction in panic symptoms and intensity as measured with the Panic Symptom Scale 9

View entire presentation