23andMe Investor Presentation Deck

Example: Number of Osteoarthritis GWAS¹ hits dramatically increase as database grows 2016 2017 2021 -log(pvalue) loga(pvalue) 12 10- Size and Scale Accelerate Target Discovery 60 1 GWAS: Genome-Wide Association Study. 3 6 10 11 12 Chromosome 78930 11 12 Chromosome 7 8 9 10 11 12 Chromosome 14 14 16 18 20 22 X 16 18 20 22 X 16 18 20 22 x Number of independent hits p<5e-8 New programs are identified through GWAS¹ hits, which increase as size of database grows 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 0 2015 2016 2017 2018 Copyright © 2022 23and Me, Inc. 2019 2020 23andMe 30

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