Avantor Results Presentation Deck

2022 full-year guidance avantor™ Organic revenue growth 1. 2. Adj. EBITDA margin expansion Adj. EPS¹ Free cash flow FY GUIDANCE: AS OF Q2 2022 4-6% >125 bps $1.43 - $1.49 >$950M YTD RESULTS 3.9% -130 bps $1.09 ~$538M FY GUIDANCE: CURRENT 2.5 - 3% 100 - 125 bps $1.38 - $1.40 ~$800M ● COMMENTS RE. CURRENT FY GUIDANCE • Updated to reflect flow through of growth assumptions ● FY core organic: 6.0 - 6.5% FY reported: 1.5 - 2.0% Change from Q2 guidance²: M&A impact: -$0.03 ● 2H organic impact: -$0.03 FX impact: -$0.013 • Flow through of operating results & FX impact • Investment in working capital to mitigate supply chain risks Adj. EPS estimate based on US GAAP diluted share count of ~680M. Numbers cited represent changes from FY Adj. EPS guidance as of Q2 2022 to current FY Adj. EPS guidance. 3. Updated to reflect current estimate for FY blended USD/EUR exchange rate (FY blended estimate: 1.12 at Q4'21, 1.09 at Q1'22, 1.06 at Q2'22, 1.04 current). 10

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