Certara Investor Day Presentation Deck

Streamlining trials and optimizing outcomes Biosimulation Use Case Examples Nonclinical Discovery Clinical Improve target selection Identify safety risks early Replace, reduce and refine animal studies Inform design of subsequent experiments Determine first-in-human dosing Waive drug interaction studies Optimize dosing for special populations Streamline or waive bioequivalence studies Benefits Fail faster Streamline or waive animal and human studies Help increase safety and efficacy Cut time and cost 9 CERTARA

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