23andMe Investor Presentation Deck

Example: Number of Osteoarthritis GWAS¹ hits dramatically increase as database grows 2016 2017 2021 log10 (pvalue) log10(pvalue) log10(pvalue) 12- 10- Size and Scale Accelerate Target Discovery 15- 1 GWAS: Genome-Wide Association Study. 2 3 4 5 6 9 10 11 12 Chromosome 7 8 9 10 11 12 Chromosome 7 8 9 10 11 12 Chromosome 14 14 16 18 20 22 X 16 18 20 22 X 16 18 20 22 X Number of independent hits p<5e-8 New programs are identified through GWAS¹ hits, which increase as size of database grows 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 0 2015 2016 2017 2018 Copyright © 2022 23and Me, Inc. 2019 2020 23andMe 31

View entire presentation