Kymera Results Presentation Deck

Skin PK: KT-474 Has High Skin Concentration In Patients at Day 28 Higher than MAD3 HV n=11 for Day 28 and n=10 for Day 42 KT-474 Concentration (ng/g) Mean (± SE) 500 KYMERA ©2022 KYMERA THERAPEUTICS, INC. 400 300 200 100 0 Part C: 75 mg QD (fed)* Day 28 386 (± 103) Day 42 135 (± 33.8) PAGE 34

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