Ocuphire Pharma Investor Presentation Deck

Change in DRSS Score by Patient by Eyes 16% Patients in Placebo Treatment Group had Binocular 3-Step Worsening Improvement Worsening Change in DRSS -6 -4 -3 Ń 2 3 -2,-2 -0,-3 -2,-1 -1,-1 -1,-1 -1,-1 0,-2 0₂-2 Presented on 8/1/23 at ASRS Placebo Binocular Change from Baseline @Week 24 (MITT LOCF) -1,0 -1,0 -1,0 0,-1 -1,0 -1,0 | | | | | | 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 Patients (n=50) 3,-3 DRSS Bar Legend Green: Both Eyes Improving Blue: 1 Eye Improving and 1 Eye Unchanged Purple: 1 Eye Improving and 1 Eye Worsening Orange: no change OU Gray: 1 Eye Worsening and 1 Eye Unchanged Red: Both Eyes Worsening -0,1 0,1 0,1 1,0 0,1 0,1 0,1 2,-1 0,2 3,0 0,3 3,0 -2,5 0,4 1,3 2,2 2,4 26

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