ProSomnus SPAC Presentation Deck

OSA is Highly Prevalent and Associated with Major Health Consequences ■ OSA is the recurrent collapse of the airway during sleep resulting in oxygen shortages and subconscious arousals OSA is associated with comorbidities and excessive daytime sleepiness ■ CPAP, which forces air down the patient's throat, is the primary incumbent therapy ■ ■ ■ OSA is underdiagnosed, yet diagnosis is getting easier due to increased awareness and technology WHAT IS SLEEP APNEA Initiatives include public awareness and advanced in-home screening technology COMORBIDITIES¹ Untreated OSA is associated with a 4-5 fold increase in mortality² Stroke 63% Morbid Obesity 77% Type 2 Diabetes 72% Drug-Resistant Hypertension 83% Congestive Heart Failure 76% Angina / CAD 57% Atrial Fibrillation 49% Open Airway O Obstructed Airway NON-OBSTRUCTED AIRWAY PROSOMNUS SLEEP TECHNOLOGIES Tongue OBSTRUCTED AIRWAY Tongue 1. Provided at fryedental.com/services-sleep-apnea, accessed 2021 Dec 21; copyright 2018 DREAMSLEEP, LLC, statistic sources available at dreamsleep.rest/resources 2. Young, Terry & Finn, Laurel & Peppard, Paul & Szklo-Coxe, Mariana & Austin, Diane & Nieto, F & Stubbs, Robin & Hla, Khin. (2008). Sleep Disordered Breathing and Mortality: Eighteen-Year Follow-up of the Wisconsin Sleep Cohort. Sleep. 31. 1071-8. 10.3410/f.1120845.580647 8 STRICTLY CONFIDENTIAL

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