Dare Bioscience Investor Presentation Deck
12
Women's Health - Compelling Markets Where Innovation Matters
Contraception
~73 Million women ages 15-49¹
1st hormonal monthly IVR, NuvaRing, ~$900M at peak²
1st hormonal IUD, Mirena franchise, ~$1.2B at peak³
1st copper IUD, still ~$200M/yr 40 years post launch4
Sexual Health
- No FDA approved product for female sexual arousal
disorder, despite similar prevalence to erectile dysfunction
1st drug indicated for ED, Viagra, $2B at peak³
Source: CDC National Survey for Family Growth, zos5-20sy dataset, cdc.gov.
https://sec.report/Documentioooo210150-20-00000
https://www.bayer.com/en/bayer-ag-annual-report-2009.pdfx. includes sales for Mirena", Kyleena" and Jaydess" /Skyla
https://investor.coopercos.com/static-files/zzco58fe-sd74-4899-332-6dbaz58b2afa
https://www.cdc.gov/std/by/stats.htm: Bacterial vaginosis product data: http://www.clindesse.com/pdf/Pl.pdf, http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/2052235000lbl.pdf,
http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/2052235000lbl.pdf
https://media.bayer.com/baynews/baynews.nsflid 6F1503CB434A4B₁0C25874200273606?open&refirrefindcd#text-Theldomostizofrequently reportedzoand, life's activity%2Cléopersonally and professionally.
https://www.wsi.com/articles AL-HEB-26
Organon 102032 earnings call
https://www.reuters.com/article/us-pfizer-britain-viagraluk-gives-pfizer-worlds-first-over-the-counter-viagra-approval-idUSKBN=DSZ
https://www.harriswilliams.com/sites/default/files/content/fertility_industry overview_2015.05.19.vso.pdf
https://www.latimes.com/business/story/2022-02-ap/makena-covis-premature-birth-pregnant-womens-health
https://www.ferring.com/wp-content/uploads/sites/16/2021/03/Ferring-2020-Annual-Report-2020_Final_Digital_Spreads.pdf
Vaginal Health
- Bacterial vaginosis affects ~21 million women in the US;
but current Rx clinical cure rates 37-68%5
- 47 million new entrants to menopause and post-
menopause market each year6
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1st estrogen hormone therapy, Premarin, ~$2B at peak7
Fertility
- 15M babies (11.1% of all live births) are born pre-term every year⁹
- U.S. fertility pharmaceutical sector, estimated to be $1.5B¹⁰
1st preterm birth drug, Makena, -$400M at peak¹¹
IVF follicle stimulating hormone + luteinizing hormone,
Menopur, -$570M in 2020¹2
What are the next big ideas?
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