Investor Presentaiton
Demographics and Baseline Characteristics
Age, median (range), years
Female, n (%)
Dato-DXd (n=365)
56 (29-86)
360 (99)
ICC (n=367)
54 (28-86)
363 (99)
Daiichi-Sankyo
Race, n (%)
Ethnicity, n (%)
Black or African American / Asian / White / Other*
4 (1) 146 (40) 180 (49) / 35 (10)
7 (2) / 152 (41) /170 (46) / 38 (10)
Hispanic or Latino / Not Hispanic or Latinot
40 (11)/322 (88)
43 (12) / 318 (87)
Prior lines of chemotherapy, n (%)
1/2
229 (63) / 135 (37)
225 (61) / 141 (38)
Prior CDK4/6 inhibitor, n (%)
Yes/No
299 (82) / 66 (18)
286 (78) / 81 (22)
Prior taxane and/or
anthracycline, n (%)
Taxane and/or Anthracycline
330 (90)
Neither
35 (10)
339 (92)
28 (8)
*Including not reported. "Ethnicity missing: 3 patients in Dato-DXd group; 6 patients in ICC group.
*In the inoperable/metastatic setting; one patient in the Dato-DXd group had 3 prior lines of chemotherapy; one patient in the ICC group had 4 prior lines.
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