Business Update & Financial Outlook

Q2 2023 GAAP financial results summary $ in billions, except LPS/EPS amounts Q2 2023¹ Q2 2022 Change Change Ex-FX Sales $15.0 $14.6 +3% +7% Operating Expenses $16.0 $5.3 N/M N/M Tax Rate -11.9% 12.0% -23.9pts N/A GAAP Earnings / ($2.35) $1.55 N/M N/M (Loss) per Share 1.2Q23 GAAP results include $10.2 billion or $4.02 of such charges related to the acquisition of Prometheus Biosciences. MERCK 27

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