Investor Presentaiton

Program of Data Collection Continuing ریع Clinical Study Program - additional data collation de-risks exposure to future reimbursement changes Study Name Study Type Study Sites Study Details iTrack TM Global Data Registry WCG IRB (approval number) 20200728 Prospective, multicenter, real-world registry study 20+ sites in the USA, UK, Canada, Australia, Singapore and Germany. • • 350+ patient data entries completed since mid 2022 All glaucoma severities i.e., mild, moderate and severe Study Synopsis • Independent cloud-based platform that collates efficacy and safety data for the canaloplasty procedure (iTrack TM and iTrack TM Advance) Hosted in collaboration with the International Glaucoma Surgery Registry (IGSR), the official registry partner of the European Glaucoma Society (EGS). Prospective, multicenter randomised control CATALYST Study NCT05564091 trial. MAGIC Study (Europe) NCT05786196 5+ sites in Germany, • 140 patients in total (recruitment ongoing) Mild-moderate glaucoma Canaloplasty performed in combination with cataract surgery "Cataract Surgery in Conjunction with Canaloplasty via an Ab- Interno Approach in Patients with Mild to Moderate Primary Open-Angle Glaucoma" Comparison of iTrack TM Advance performed in combination with cataract surgery, compared to cataract surgery alone. . the Netherlands and Australia Prospective, multicenter randomised control trial. 5+ sites in the UK, Italy, Spain and Germany. • 78 patients in total (recruitment ongoing) • Mild-moderate glaucoma • Canaloplasty performed as a standalone procedure Multicenter Glaucoma Study Investigating Standalone Canaloplasty Comparison of the iTrack TM Advance as compared to the OMNIⓇ Surgical System (Sight Sciences). nova-eye.com | 20

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