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Investor Presentation

43 Investor presentation First six months of 2022 Novo Nordisk has 55% of the global GLP-1 market, while GLP-1 penetration of diabetes volume varies across regions 80% 60% 40% 20% 0% Novo NordiskⓇ GLP-1 market growth and Novo Nordisk market share >6 million people, 4% of diabetes prescriptions, use a GLP-1 with large differences across markets Million scripts May 2019 Global: 4% 8 62% OZEMPİC semaglutide injection RYBELSUS semaglutide tablets 55% 6 55% 46% 4 2 0 May 2017 2022 -NN market share NN share of growth EMEA -Market growth NN growth North America Patient share based on data for the USA, the UK, Germany and France only. Source: IQVIA MAT value (spot rate), May 2022 9% 2% 2% 4% 2022 Region China Rest of World GLP-1 share of diabetes prescription EMEA: Europe, Middle East and Africa; Region China covers Mainland China, Taiwan, and Hong Kong Source: IQVIA MAT, May 2022
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