American Thoracic Society - Sanofi Investor Call slide image

American Thoracic Society - Sanofi Investor Call

Opportunity to bring breakthroughs to large number of in-need COPD patients Eligible patients in G7 countries Large biologics eligible patient population in G7 COPD patients 1.7m countries Asthma patients 1.9m Biologics penetration in COPD >35% Significant growth of At peak biologics penetration in COPD expected No biologics Today Source: Sanofi Internal Analysis Dupixent and itepekimab are under investigation in COPD and not yet approved by any regulatory agency to treat this indication 47 ATS Investor Call sanofi Potential first-in-market with DupixentⓇ • Impressive data in high need, lethal disease Addressing ~35% of severe patients at launch Near-term expansion with itepekimab • Expanding patient opportunity by >2X Two complementary, potential best-in-class agents • Reaching 80+% of the severe population Maximized with proven ability to execute
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