Investor Presentaiton

Investor Presentation First nine months of 2018 Slide 92 Healthcare cost associated with obesity expected to increase Global healthcare cost related to obesity expected to increase by 50% by 2025 +50% USD ~0.8 trillion USD ~1.0 trillion USD ~1.2 trillion • • • • Increase in healthcare costs primarily driven by obesity-related comorbidities Today, 650 million people have obesity globally By 2025, ~1 billion people are expected to have obesity If left untreated, by 2025, the cost of treating complications of obesity is expected to reach USD ~550 billion in the USA and USD ~1.2 trillion globally The increased healthcare costs are primarily driven by obesity-related comorbidities such as type 2 diabetes and cardiovascular disease 2017 2020 2025 Source: World Obesity Federation, 2017 changing diabetes® Source: WHO, October 2017; World Obesity Federation, 2017 novo nordisk

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