Investor Presentation H1 2023

156 Investor presentation First six months of 2023 Novo NordiskⓇ Novo Nordisk pledges to reach net-zero emissions across the entire value chain by 2045 1,000 tonnes CO2 Emissions from Scope 1, 2 and 31 -83% -16% 72 76 Key initiatives to reduce CO2 emissions across all three scopes Scope 1 - Direct emissions from own sources (16% reduction vs H1 2019) Company cars: 100% electric or plug-in hybrid electric cars by 2030 Energy: Ongoing transition to renewable energy in production facilities resulted in reduced emissions 43 40 40 39 9 H1 2019 (baseline)² H1 2022 Targets: • 2030: Zero emissions from operations and transportation³ 36 7 H1 2023 68. -6% Scope 2 - Indirect emissions from purchased energy (83% reduction vs H1 2019) • Production: Sourcing 100% of renewable power at production sites since 2020 Scope 1 Scope 2 Scope 3 - Other indirect emissions across value chain (6% reduction vs H1 2019) Suppliers: >400 key suppliers have committed to source renewable power Product distribution: Alliances with various providers for Sustainable Aviation Fuel that will reduce emissions from air transport significantly Scope 3 2045: Net zero emissions across full value chain 1 Scope 3 emissions are limited to emissions from business flights and product distribution. 2 In 2019, some emission categories were only reported on an annual basis. For these categories, the quarterly emissions have been estimated based on the full-year results. ³ CO2 emissions from operations and transportation represent the emissions from production, offices and labs, cars, business flights and product distribution.

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