Leqvio FDA Approval slide image

Leqvio FDA Approval

We are building on our strength in cardiovascular to fundamentally improve and extend patients' lives 2015 Entresto sacubitril/valsartan Essential first choice for chronic heart failure ~15m patients 2021 ~2025 LEQVIO pelacarsen inclisiran Potential to tackle LDL-C in ASCVD at scale (TQJ230) Potential to lower CV risk for people with elevated Lp(a) ~60m patients High unmet need: CV disease leading cause of mortality Strong worldwide commercial and scientific presence Deep understanding of customer needs across primary and specialty care LDL-C - Low Density Lipoprotein Cholesterol ASCVD Atherosclerotic Cardiovascular Disease CV - Cardiovascular Lp(a) Lipoprotein(a) Note: Dates refer to US approval for EntrestoⓇ and LeqvioⓇ, to submission for pelacarsen. Population numbers refer to US & EU5 (Germany, France, Spain, Italy, UK). Source: Decision Resources Group. 5 Leqvio® FDA Approval | December 23, 2021 | Novartis Investor Presentation 1 NOVARTIS | Reimagining Medicine
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