Investor Presentation Full Year 2021 slide image

Investor Presentation Full Year 2021

22 Investor presentation Full year 2021 Novo NordiskⓇ Novo Nordisk's opportunity is in the large unmet needs across all therapy areas in scope DIABETES ~463 million -6% OBESITY ~650 million -2% HAEMOPHILIA ~0.5 million -25% People with diabetes People in good control People with People medically obesity treated People with haemophilia People being treated OTHER SERIOUS CHRONIC DISEASES * Gro 80% of diagnosed NASH patients are obese and 35% have T2DM 70% of diabetes patients die from atherosclerotic CVD 40% of patients hospitalised for heart failure are diabetic ~50% of the total CKD population suffers from diabetic nephropathy NASH: Non-alcoholic steatohepatitis, T2DM: Type 2 diabetes mellitus, CVD: Cardiovascular disease, CKD: Chronic kidney disease. Note: All figures are global and good control defined as A1C that is less than 7% Source: International Diabetes Federation; Diabetes Atlas 9th Edition 2019, IQVIA MIDAS 2017, World Federation of Haemophilia - Annual survey 2018; Abera SF et al. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015, 2017; Heart Disease and Stroke Statistics, American Heart Association, 2017; Williams CD et al. Prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis among a largely middle-aged population utilising ultrasound and liver biopsy, 2011; Addressing the global burden of chronic kidney disease through clinical and translational research, 2014
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