Investor Presentaiton

Cash inflows from partnerships Product Regional marketing partners Total upfront & milestone payments to date (EUR) Total potential future milestones (EUR)¹ Total royalty &/or supply cash in from inception to date (H1 2023) (EUR) ESTELLEⓇ 15 128 million 296 million 21 million DONESTAⓇ 2 55 million 32 million 0 million MYRINGⓇ 20 20 Total 12 million 0 million 9 million 198 million 328 million 1 additional potential upside of high single-digit to low double-digit per annum royalties based on sales 30 million Mithra Investor Presentation - November 2023 4

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