Novavax Global Commercial Operations and COVID-19 Vaccine Update

COVID-19 variant strain development in advance of strain selection Origin Straine Wuhan Omicron B.1.15200 novavax Note: As of February 28th, 2023. BA20 BAA0- BAGO BA.2.75 XBBO OBA.2.12.1 BA.4.6 OBA.5.2.6 OBF.7 OBF.11 BQ 10 BQ.1.1 OCH.1.1 -OBA.2.75.2 OBN.1 OXBB.1.5 -OB.1.617.2 BA:10 BA.1.1 Delta Variant cloned and produced in laboratory Priority #1 Variant of interest progressing to GMP manufacturing © 2023 NOVAVAX. All rights reserved. 16

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