Corporate & Investor Presentation

Reducing mortality with PAP therapy U.S. multicenter, population-based cohort study . Study included 392 patients with sleep apnea, with 11 years of follow-up • Positive airway pressure therapy associated with a 62% lower risk of all-cause mortality Death rate was twice as high for persons who did not receive positive airway pressure therapy - (24.7 vs 12.8 deaths per 1000 person years, p = 0.03) Lisan Q et al. JAMA Otolaryngol Head Neck Surg 2019 42 2022 ResMed | Corporate & Investor Presentation - updated 28APR22 Proportion Surviving, % 100 90 80 70- 60 0 Sleep Heart Health Study HR, 0.38 (95% CI, 0.18-0.81) PAP prescribed PAP not prescribed 5 10 15 20 Time, y ResMed

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