Investor Presentation

(0) M&A - Our Strict Acquisition Criteria Technology leadership Strengthens, expands Repligen's presence Underinvested in a key area (commercial, R&D, systems, infrastructure) Strong revenue growth, margins in line with or above corporate average Potential to be accretive to adjusted EPS in first full year post-acquisition Acquisition Refine (assets) Atoll GmbH TangenX Spectrum C Technologies ARTESYN* (+NMS, EMT) Polymem S.A. Avitide Inc. *largest of 3 acquisitions in 2020 Repligen investments in... PREPLIGEN INSPIRING ADVANCES IN BIOPROCESSING Commercial Operations ✓ ✓ ✓ ✓ ✓ R&D ✓ ✓ > ✓ ✓ ✓ Together acquisitions through 2020 contributed >55% of 2020 revenue 12

View entire presentation