Investor Presentaiton

Investor presentation Full year 2018 Slide 65 Novo Nordisk has strengthened its insulin volume market share in Region Latin America Region Latin America insulin market by segment Region Latin America modern and new- Novo Nordisk generation insulin volume shares Eli Lilly Sanofi Other Device penetration tMU CAGR volume¹: 10.2% 18 CAGR value¹: 6.9% 15 12 9 16 3 0 Nov 2013 - Modern insulin penetration Penetration 50% 70% 60% 40% Fast-acting 50% Premix 30% 40% 30% 20% Long-acting 20% 10% 10% 0% 0% Nov 2018 Nov 2013 1 CAGR for 5-year period Note: IQVIA covers the following 4 markets in Latin America (retail data): Argentina, Brazil, Colombia and Mexico Source: IQVIA monthly MAT data Nov, 2018 volume and value figures Note: Only top-3 shown Source: IQVIA monthly MAT data Nov, 2018 volume figures 46% 26% 16% 12% Nov 2018 novo nordisk

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