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Investor Presentaiton

ESTELLE® – addressing women's unmet need and improving women's contraceptive experience Improving contraceptive experience ➤ Reliable contraceptive efficacy ➤ Excellent cycle control' Proven superiority in comparison to Ethinylestradiol containing COCs ➤Improved quality of life & high user satisfaction ➤ Potential positive skin effect ➤ Low risk of drug-drug interaction² Addressing unmet needs Favorable safety profile Low impact on all markers of coagulation suggest low clotting risk Minimal increase of triglycerides ➤ Minimal impact on glucose metabolism ➤Minimal impact on breast tissue expected based on preclinical data³ 1) Kaunitz et al,. Contraception 2022; Jensen et al., Contraception 2022; Archer et al., JCM 2022 2) Foidart et al., NAMS 2022 3) Gallez et al. Cancers 2021 Mithra Investor Presentation - November 2023 18
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