Investor Presentaiton

Novo Nordisk Annual Report 2023 ENVIRONMENTAL SOCIAL GOVERNANCE Double materiality assessment Introducing Novo Nordisk Strategic Aspirations Risks Management Consolidated statements Additional information Preliminary assessment of material ESG topics GOVERNANCE Business conduct Bioethics Novo Nordisk conducted an initial double materiality assessment in 2023 to determine which environmental, social and governance (ESG) topics are material for the company. This assessment considers both the impact of Novo Nordisk's business on society and the environment (impact materiality) and how ESG matters affect the company (financial materiality). The assessment involved experts and leaders from within Novo Nordisk, as well as input from external stakeholders, such as patient organisations, suppliers and investors. The purpose of the assessment is to prepare for the implementation of the Corporate Sustainability Reporting Directive (CSRD) in 2024. It covers all topics defined in the CSRD, along with other ESG topics relevant to Novo Nordisk. The table on the right shows the preliminary, aggregated results of the assessment, and includes both current and potential ESG topics from a short-, medium- and long-term perspective. The ESG topics will help guide the preparation of the company's ESG reporting from 2024 onwards. Many of the preliminary, material ESG topics reflect Novo Nordisk's strategic sustainability focus. For social topics, this includes our efforts to provide access to life-saving medicines without compromising safety or quality, improve patients' quality of life and support resilient healthcare systems. Workers' wellbeing, both within and outside of our operations, reflects the importance of remaining a relevant and attractive workplace while respecting adequate working conditions. We also consider our local impact in the communities we operate in and pay tax where value is created. The preliminary, material environmental topics reflect Novo Nordisk's environmental initiatives to reduce carbon emissions and promote a circular economy, for example on plastic. ESG topics such as biodiversity and water reflect the company's dependence on nature-based resources. To this end, Novo Nordisk is already increasing sustainability efforts directly related to nature and biodiversity. Moreover, the company strives to limit any negative effects resulting from its business operations, including pollution. Business conduct reflects our efforts to adhere to the highest ethical standards, including bioethics. Overall, Novo Nordisk aims to be respected for its contributions to society and to build trust through its sustainability efforts. ENVIRONMENTAL Climate change Resource use and circular economy Water and marine resources SOCIAL Patient protection¹ and quality of life Own workers Workers in the value chain Biodiversity and ecosystems Pollution Sustainable tax Affected communities 1. Includes topics related to consumers and end-users. 12 12

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