Investor Presentation Q1 2023

156 Investor presentation First three months of 2023 Novo NordiskⓇ ESG is integrated in reporting and remuneration as well as recognised externally ESG is included in integrated reporting and short- and long-term remuneration We strive to adhere to sustainability frameworks for our ESG reporting ESG rankings by third-party agencies recognise Novo Nordisk's efforts Rating agency novo nordisk Ⓡ Annual Report 2022 B Hageman oighis one s one of Denmark angesteng people with spurt here with fis son Lars, who also has type 1 diabetes and his grandchildren hom the leto Clane and Hager Novo Nordisk AS-Novo Ale 1.2880 and Dermark-237 Remuneration Report 2022 rik Hageman (back in the middle, his son Lars Hageman Perborg and grandd (from the left Clara Holger and bike Hogenan Pinborg Erand Lars have type tubes Novo Nordisk A-Novo Ale, 2880 Bigad Dermaak-c242567 ESG Portal recommeding a suitable bures. No u dha means that we add value to ta mposite way reflectesin our Anicles of Asoonton and the Novo Nordisk Way The ESG Pental provides oonaut our approach and performance Severe 56 | SASB STANDARDS Now part of IFRS Foundation MSCI ESG RATINGS AAA CCC B BB BBB A AA AAA SCIENCE BASED TARGETS DRIVING AMBITIOUS CORPORATE CLIMATE ACTION TCFD SUSTAINABLE DEVELOPMENT GOALS AAA SUSTAINALYTICS Top 13% in industry group 'pharmaceuticals' CDP DISCLOSURE INSIGHT ACTION A LIST 2022 CLIMATE A (Climate) A- (Water) access to medicine Index Ranked 11th out of 20 companies CDP: Carbon Disclosure Project; MSCI: Morgan Stanley Capital International; TCFD: Taskforce on Climate-related Financial Disclosures; SASB: Sustainability Accounting Standards Board

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