Investor Presentaiton
Dengue is currently the main viral disease transmitted by arthropods in terms of morbidity and
mortality. Dengue viruses are transmitted mainly by Aedes aegypti mosquitoes and to a lesser extent by
Aedes albopictus. Symptomatic infections can be mild, moderate and severe, which can lead to death.
The geographical distribution of dengue largely reflects the distribution of the vector. The geographical
expansion and magnitude of the disease in recent decades has paralleled rapid population growth,
unplanned urbanization and the unprecedented increase in population mobility.
Climate is an important determinant of the temporal-spatial distribution of dengue. It is known that elevated
temperatures increase the speed of development of the larvae and consequently of the adult mosquito,
which can lead to an increase in the rate of bite and the rate of replication of the virus in the mosquito, which
leads to vectors. They become infective sooner and itch more frequently. Variability in rainfall influences the
availability of vector breeding sites and consequently the abundance of the vector. Humidity influences the
half-life of the vector and potentially the transmission. The existence of four dengue serotypes, the duration
of cross-protection between serotypes, the phenomenon of ADE (antibody-dependent amplification) also
influence the dynamics of transmission and the severity of the disease.
The authorities of the Ministry of Public Health reported that in the first quarter of 2016 at least 10 cases
of Zika had already been confirmed through the Center for Disease Control in Atlanta, United States of
America (MISPAS, 2016) (18). The Zika virus - also transmitted by the Aedes aegypti mosquito - is the same
that transmits dengue and chikungunya.
ILLUSTRATION 2: Seasonal variation pattern of dengue cases according to climate variability described by
the Economics of Climate Change in Central America and the Dominican Republic (ECC CARD) for the Third
National Communication from the Dominican Republic to the United Nations Framework Convention on
Climate Change (TCNCC) (15).
Valor del IB1,t,Santo Domingo (R)
□ Outliers (R)
Extremes (R)
☐ Caso Dengue (L)
□ Outliers (L)
* Extremes (L)
12000
10000
Casos de Dengue en Santo Domingo
800
600
600
400
2000
H
HOH
H
ㅁ
☐
Ho!
2.00
1.50
1.00
I
0.50
ㅁ
0.00
-0.50
-1.00
-1.50
Valor del IB1,t,Santo Domingo
-2.00
-2.50
☐
-3.00
☐
-3.50
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Dominican RepublicView entire presentation