Investor Presentation - First Nine Months of 2016

Investor presentation First nine months of 2016 Slide 40 Stable global insulin volume growth Regional insulin volume growth - USA Pacific Europe World Int. Operations Region China 30% 100% 25% 80% 20% 15% 10% 60% 40% 5% 0% Aug 2011 3.7% 20% 0% Aug 2016 Note: Data is sensitive to changes in IMS data collection and reporting methodology Source: IMS Monthly MAT August, 2016 volume figures changing diabetes® Regional insulin volume market split USA Europe Int. Operations Region China Pacific 8% 9% 21% Aug 2011 Note: Data is sensitive to changes in IMS data collection and reporting methodology Source: IMS Monthly MAT August, 2016 volume figures 34% 28% Aug 2016 novo nordisk

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