Investor Presentaiton

H1'22 Highlights Branches 1,373 00 MA Employees Total customers (mn) 2 Digital customers (mn) Customer loans (€ bn) 28,236 ■ 20.5 5.8 40 Customer funds (€ bn) 49 ☐☐☐ Underlying attributable profit (€ mn) 546 ROTE¹ 33.2% Santander Mexico 'Santander México, one of the leading financial groups in the country, focused on commercial transformation and innovation' Strategic priorities ■■ To become the leading bank in terms of customer experience, leveraging new tools and improved processes Maintain strong growth rates in loyal and digital customers, as well as increase presence in high-potential businesses ■ Strengthen the corporate business to maintain our position as market leaders in value-added products Further the technological transformation and digitalization, through the execution of a multi-year plan to improve the operating model (1) Adjusted ROTE: adjusted based on Group's deployed capital calculated as contribution of RWAs at 12%. Using tangible equity, ROTE is 15.8%. Customer loans: gross loans excluding reverse repos. Customer funds: customer deposits excluding repos + marketed mutual funds. More information at https://www.santander.com/en/about-us/where-we-are/santander-mexico 26

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