Q1 2022 Results slide image

Q1 2022 Results

Company overview Financial performance Financial review 2022 priorities Innovation: Pipeline overview Appendix Innovation: Clinical trials References Abbreviations Key milestones of pipeline assets with significant sales potential with approval by 2026 Selected assets, most advanced and key indication(s) approved by 2026 High strength of evidence Iptacopan PNH Iptacopan C3G Iptacopan aHUS Iptacopan IgAn Remibrutinib CSU 2022 Ph3 readout 2023 Submission 2024 2025 2026 High strength of evidence Ensovibep Coronavirus infection 2022 Submission 2023 2024 2025 2026 Ph3 read/sub Scemblix Approval Scemblix CML 1L Ph3 readout Submission Ph3 readout Submission Vijoice PROS Approval Ph3 read/sub Piqray Ovarian Cancer Ph3 read/sub Ph3 read/sub Piqray TNBC Ph3 read/sub Ph3 read/sub Piqray HER2+ adv BC Ph3 read/sub Ph3 readout Submission Tislelizumab Submissions and approvals of several indications Ph3 read/sub Remibrutinib MS Zolgensma SMA IT Ligelizumab Food Allergy Kisqali Ph3 read/sub YTB323 2L DLBCL Ph3 start lanalumab Sjögren's Ph3 start lanalumab LN Ph3 start Cosentyx HS Cosentyx Lichen Planus Cosentyx GCA Pluvicto mCRPCR post taxane Pluvicto mCRPCR pre taxane Pluvicto tetraxetan mHSPC NME Lead 1. Event driven, could move to early 2023. 36 Investor Relations | Q1 2022 Results Moderate strength of evidence Ph3 read/sub Sabatolimab MDS 2022 Ph2 readout 2023 2024 2025 2026 Ph3 read/sub Sabatolimab AML Ph3 readout Ph3 readout Submission in 2022/23 Submission Ph3 read/sub NIS793 PDAC Ph3 read/sub Submission Ph2 readout Pelacarsen CVRR Ph3 read/sub Submission Ph3 read/sub Canakinumab Adj. NSCLC Ph3 readout Submission Ociperlimab Approved UNR844 Presbyopia Ph3 start Ph2 readout BeiGene option deal Submission Ph3 readout¹ Submission Ph3 read/sub Libvatrep COSP Ph2 readout Submission JDQ443 NSCLC JDQ443+TNO155 NSCLC Ph3 start Submission Ph3 start Submission ✓ NOVARTIS | Reimagining Medicine
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