Investor Presentation First Nine Months of 2023

121 Investor presentation First nine months of 2023 Insulin market size and volume market share in EMEA Insulin market share and market size (DKK billion) Total 48% Long- acting 41% Fast- 55% 12 acting 73% Premix 3 44% Human 3 19 Novo Nordisk Competitors Market growth¹ A Market share 60% 37 -1.4% -0.3% 1.4% +0.0% 40% Insulin volume: Market share EMEA 10% 47% 5% 0% -0.2% +0.0% -3% 20% -5% -4% -11.1% -0.8% 0% Aug 2020 NN market share -13.4% +0.3% -10% Aug 2023 Market growth (right axis) NN growth (right axis) 1Market growth is YTD current vs YTD previous year Source: IQVIA, Aug 20223 LHS graph - Value, RHS Graph - Volume, MAT, Europe, Middle East & Africa, Share of growth not depicted due to too high numbers; NN: Novo Nordisk; Market values are based on the list prices

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