Q1 2022 Results slide image

Q1 2022 Results

Company overview Financial review 2022 priorities Appendix References 1 GROWTH Leqvio® US launch in line with expectations Driving broad customer engagement of prioritized HCPs reached¹ increase in unaided awareness² CE Z KK LEQVIO Establishing access and acquisition pathways >35 of ~200 prioritized systems have ordered Leqvio³ of corporate AIC accounts have purchased Leqvio³ >90% >2x ~55% 2 doses* a year seen as key differentiator2 >30% of customers have placed repeat orders³ DTC initiated -50% lives have coverage aligned to label4 Permanent J-code (J1306) has been granted and will go into effect July 1, providing greater reimbursement confidence HCP Healthcare Professional AIC - Alternative Injection Center 1. Internal tracking. Data on file 2. Compared to Q4 2021. Based on market research. Data on file 3. Based on sales data, Data on file. 4. Internal tracking of Formal medical policies published to date and early reimbursement experience. Data on file. *LEQVIO® is administered initially, again at 3 months, and then once every 6 months. 13 Investor Relations | Q1 2022 Results ✓ NOVARTIS | Reimagining Medicine
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