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Investor Presentaiton

Strong business momentum Diversified portfolio growth Efficient compounding engine Sustainable long-term growth Consistent attractive returns amplified with conservative leverage Estimated unlevered returns Rolling 5-year investment periods (%) (1) Leverage benefit to return profile Based on investment periods since 2012 (%) (1) 25 High Teens to Low 20s % 25 Investment Targets: 20 High-single to low-double digit % for approved therapies Teens % for development-stage therapies 20 Low Teens Blended % 15 15 Low Teens % Average Returns 10 5 10 5 Benefit of conservative leverage Roughly 1/3 of royalty acquisitions funded with low-cost debt 0 0 '12-'16 '13-'17 '14-'18 '15-'19 '16-'20 '17-'21 Royalty Pharma Unlevered Returns Royalty Pharma Levered Returns Proven track record of consistent returns, amplified with conservative leverage, creating value in excess of cost of capital ROYALTY PHARMA 1. Illustrative returns reflect a combination of actual results and estimated projected returns based on analyst consensus sales projections (where applicable). 97
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