Investor Presentation Full Year 2021

90 Investor presentation Full year 2021 Growth momentum has increased driven by demographics and the Market Fit approach International Operations is diverse and covers 190 markets 14% 430M live with diabetes 10% 570M live with obesity 6% 5% IO's share of revenue FY 2021 NAO 48% ΙΟ 52% 2% Historic growth has been in the range of 4-8% 14% mall 30% 20% 10% Novo NordiskⓇ Growth momentum has benefitted from the Market Fit approach 0% 2014 2021 Nov Market Fit approach 2018 Growth rate range introduced NAO: North America Operations; IO: International Operations; Share of Growth not depicted due to high numbers; FY: Full Year NN Diabetes market share Market growth NN Diabetes growth 25% 14% 6% Nov 2021

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