Investor Presentaiton

INVESTOR 20 DAY 23 Screening eligible individuals regularly engage with healthcare providers Blood-based screening is patient preferred and fits seamlessly into routine care Doctors visit for any reason in the last 12 months1 GUARDANT™ Ages 50 - 64 Ages 65+ 87% 95% Blood draw in the 85% last 12 months² 1.https://wwwn.cdc.gov/NHISDataQueryTool/SHS_adult/index.html. 2. Guardant Patient Segmentation, Q3 2022, N=1932 117

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