Fourth-Quarter and Full-Year 2019 Orphan and Rheumatology Segment Results slide image

Fourth-Quarter and Full-Year 2019 Orphan and Rheumatology Segment Results

GAAP to Non-GAAP Reconciliation Net Income (Loss) and Non-GAAP Net Income - Three and Twelve Months Ended December 31 HORIZON $ in thousands Three Months Ended December 31, 2019 2018 Twelve Months Ended December 31, 2019 2018 GAAP net income (loss) Non-GAAP adjustments: Acquisition/divestiture-related costs $ 592,769 $ 101,648 $ 573,020 $ (38,380) Restructuring and realignment costs 942 204 (1,710) 462 3,556 237 4,396 15,350 Amortization and step-up: Intangible amortization expense 57,662 61,125 230,424 243,634 Inventory step-up expense 99 89 17,312 Amortization of debt discount and deferred financing costs 5,533 5,872 22,602 22,752 Impairment of long-lived assets 10,847 46,096 (Gain)/Loss on sale of assets (30,682) 10,963 (42,985) Share-based compensation 24,149 27,878 91,215 114,860 Depreciation 2,159 1,499 6,733 6,126 Litigation settlements 1,000 5,750 Upfront, progress and milestone payments related to license and collaboration agreements 9,073 (10) Fees related to refinancing activities 855 854 2,292 937 Loss on debt extinguishment - 58,835 Drug substance harmonization costs 63 1,275 457 2,855 Charges relating to discontinuation of Friedreich's ataxia program (145) (2,940) 1,076 (1,464) Total of pre-tax non-GAAP adjustments 91,422 74,579 438,552 435,609 Income tax effect of pre-tax non-GAAP adjustments (14,277) (57,961) (66,568) (45,186) Other non-GAAP income tax adjustments (553,334) (1,499) (554,786) (37,392) Total of non-GAAP adjustments (476,189) 15,119 (182,802) 353,031 Non-GAAP Net Income $ 116,580 $ 116,767 $ 390,218 $ 314,651 47
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